---What’s the matter ________ your sister?
---She has a________ cold.
A．with; badB．on; badC．with; badlyD．on; badly
A

試題分析：句意：你的妹妹怎么了？她患了重感冒。What’s the matter with sb?……怎么了？用介詞with，have a bad cold患重感冒，故選A。
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