—Doctor, ____________should I take this medicine?
—Twice a day.
A. what time         B. how much        C. how often
C

試題分析：句意為：---醫(yī)生，我應該多久服一次這個藥？---每天兩次。what time ：提問時間，什么時候； how much：提問數(shù)量、價格多少， how often：提問動作發(fā)生的頻率，多久一次。根據(jù)語境可知應選C。
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